The PROPEL Tech Hub, led by the Ben Franklin Technology Partners of Southeastern Pennsylvania, aims to become a global leader in end-to-end precision medicine. This Tech Hub will leverage the region’s density of life sciences assets and research and development expertise to weave together disparate technology applications: biotechnology, medical technology, genomics, synthetic biology supported by artificial intelligence, machine learning, robotics, and more. Together, these tech-enabled efforts will deliver new ways to diagnose, prevent, and treat disease, increasing evidence-based technology applications that improve morbidity and mortality and decrease health disparities.